Methodologic Issues when Estimating Risks in Pharmacoepidemiology
نویسندگان
چکیده
منابع مشابه
Methodologic issues in epidemiologic risk assessment.
This paper reviews methodologic issues pertinent to the application of epidemiology in risk assessment and discusses concerns in the presentation of results from such an activity. Assessment of the health risks associated with occupational and environmental exposures involves four phases: hazard identification, i.e., the detection of the potential for agents to cause adverse health effects in e...
متن کاملMethodologic issues in injury case-control studies.
In this paper some methodological problems particularly relevant to case-control studies of injury are illustrated by reference to previous childhood injury case-control studies. In contrast to studies of disease, where 'person time' constitutes the observational experience of interest, in injury studies person time engaged in a particular activity to often more appropriate. The implications fo...
متن کاملRandomized clinical trials in infancy: methodologic issues.
Randomized clinical trials of early nutritional interventions in infants are necessary to establish safety and efficacy of supplementation of infant formulas with LCPUFAS for term and preterm infants. Such trials pose significant methodologic difficulties when applied to infants because of the rapidly changing development of the infant's central nervous system and its interdependence with multi...
متن کاملMethodologic Issues and Approaches to Spatial Epidemiology
Spatial epidemiology is increasingly being used to assess health risks associated with environmental hazards. Risk patterns tend to have both a temporal and a spatial component; thus, spatial epidemiology must combine methods from epidemiology, statistics, and geographic information science. Recent statistical advances in spatial epidemiology include the use of smoothing in risk maps to create ...
متن کاملHeart rate recovery: validation and methodologic issues.
OBJECTIVES The goal of this study was to validate the prognostic value of the drop in heart rate (HR) after exercise, compare it to other test responses, evaluate its diagnostic value and clarify some of the methodologic issues surrounding its use. BACKGROUND Studies have highlighted the value of a new prognostic feature of the treadmill test-rate of recovery of HR after exercise. These studi...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Current Epidemiology Reports
سال: 2016
ISSN: 2196-2995
DOI: 10.1007/s40471-016-0089-1